RESEARCH FOCUS

Application of fungal enzymes (free and immobilised) in biotechnology and food industry.

PROFESSIONAL EDUCATION

Academic and Research Career

• 2015 - PhD in Biological Sciences with biotechnology specialization in Department of Biochemistry, Maria Curie-Sklodowska University in Lublin
• 2005 - employment in Department of Biochemistry, Maria Curie-Sklodowska University in Lublin
• 2005 - MSc. degree in biological sciences with microbiology specialization in Department of Biochemistry, Maria Curie-Sklodowska University in Lublin

Postgraduate studies and training courses

• "Manager Project Research" postgraduate studies organized by University of Economics and Innovation in Lublin (2010-2011)
• "Public Relations in Research projects" postgraduate studies organized by OIC Poland and University of Economics and Innovation in Lublin (2009-2010)
• "Management of Project Research and Development Works" postgraduate studies organized by OIC Poland and University of Economics and Innovation in Lublin (2008-2009)
• Basic real-time PCR training on Applied Biosystems StepOne Instrument training carried out by Life Technologies (2012)
• „Enterprising University”, training carried out by OIC Poland, 26 – 28 February 2010, Nałęczów
• "PRINCE2® Foundation Certificate in Project Management" training carried out by Center of Managerial Solutions CRM (2011)

Workshops

• 2019 - workshops in the frame of 5th International Conference of Cell Biology “Commercialization of research” run by Centre for Technology Transfer CITTRU JU Cracow, Poland
• 2019 - workshops in the frame of 5th International Conference of Cell Biology “Image processing by diCELLa sp. z o.o.” Cracow, Poland

RESEARCH PROJECTS

1. 2016-2020 - Evaluation of antioxidant and antimicrobial potential of cellobiose dehydrogenase from fungi as a component of active packaging -  National Centre of Science - 2015/17/D/NZ9/02066 - SONATA 9 (coordinator)
2. 2011-2013 - Cellobiose dehydrogenases of selected ligninolytic fungi - National Centre of Science - 2011/01/N/NZ1/03458 - PRELUDIUM (coordinator)
3. 2015-2019 - Light influence on Cerrena unicolor metabolism - National Centre of Science – 2014/15/B/NZ9/01990 – OPUS 8 (investigator)
4. 2014-2017- Importance of Cerrena unicolor laccase in adaptation to degradation of several wood kinds in various environmental conditions - National Centre of Science - 2013/09/B/NZ9/01829 – OPUS 5 (investigator)
5. 2011-2015 - Tailored Lipidic Mesophases as Novel Functional Nanomaterials in Bioenergetics and Biosensing  - PSPB - 079/2010 – Polish - Swiss Research Programme (investigator)

 PATENTS

1. No. P.406228, 2014, Laccase from Cerrena unicolor for use in the treatment of blood cancer.
2. No. P.406573, 2014, Laccase from Cerrena unicolor for use in the treatment of cervical cancer.

HONORS AND AWARDS

Awards

• 2020 - Maria Curie-Skłodowska University Rector's award for a high-level scientific paper
• 2019 - Polish Intelligent Development Award 2019 under the patronage of the President of the Polish Patent Office, Dr Alicja Adamczak in the category: Researcher of the Future for the implementation of the project "Evaluation of the antioxidant and antimicrobial potential of fungal cellulose dehydrogenase as a component of active packaging"
• 2019 - the Medal of Commission of National Education
• 2018 - Maria Curie-Skłodowska University Rector's award for research achievements (III-rd)
• 2017 - Maria Curie-Skłodowska University Rector's award for research achievements (II-nd)
• 2017 - Bronze Medal for the Long Service 3rd. Class
• 2016 - Maria Curie-Skłodowska University Rector's award for research achievements (III-rd)
• 2014 - Maria Curie-Skłodowska University Rector's award for research achievements (III-rd)

Fellowships and conference awards

• 2018 - the best oral presentation "Cellobiose dehydrogenase as a modern biomedical tool" J. Sulej, M. Osińska-Jaroszuk, M. Jaszek, M. Grąz, A. Wójtowicz, J. Kutkowska, A. Szewczyk, A. Olszewska, 10th Conference of Adepts of Physiology, Homeostasis - microbiome - xenobiotics, Lublin, September 13-14
• 2018 - the best poster "Immobilization of cellobiose dehydrogenase in natural polymers for biomedical and pharmaceutical applications" J. Sulej, M. Osińska -Jaroszuk, M. Jaszek, A. Pawlik, K. Bonio, A. Hordyjewska, A. Olszewska, 10th Conference of Adepts of Physiology, Homeostasis - microbiome - xenobiotics, Lublin, September 13-14
• 2018 - the best poster "Rhizobium exopolysaccharide with triglycerides, cholesterol and glucose adsorbing properties" M. Osińska -Jaroszuk, J. Sulej, M. Jaszek, M. Janczarek, R. Bancerz 10th Conference of Adepts of Physiology, Homeostasis - microbiome - xenobiotics, Lublin, September 13-14
• 2011 - doctoral scholarship awarded by Department of Economics and Innovation in Office of the Marshal in Lublin under the project "Scholarships for Doctoral II"

FEATURED PUBLICATIONS

1. Osińska-Jaroszuk M., Sulej J., Jaszek M., Jaroszuk-Ściseł J. (2020) Applications of Fungal Polysaccharides, Elsevier
2. Janusz G., Pawlik A., Świderska-Burek U., Polak J., Sulej J., Jarosz-Wilkołazka A.,
3. Paszczyński A. (2020) Laccase properties, physiological functions, and evolution. International Journal of Molecular Sciences 21 (3), 966, https://doi.org/10.3390/ijms21030966
4. Olszewska K., Olszewska A., Rogalski J., and Sulej J. (2020). Biotechnological and biomedical applications of fungal cellobiose dehydrogenase. Advancement of microbiology, 59 (1), 75-86.
5. Sulej J., Osińska-Jaroszuk M., Jaszek M., Grąz M., Kutkowska J., Pawlik A., Chudzik A., and Bancerz R. (2019) Antimicrobial and antioxidative potential of free and immobilised cellobiose dehydrogenase isolated from wood degrading fungi. Fungal biology, 123(12), 875-886, https://doi.org/10.1016/j.funbio.2019.09.007
6. Pawlik A., Jaszek M., Sulej J., and Janusz G. (2019) Light-regulated synthesis of extra-and intracellular enzymes related to wood degradation by the white rot fungus Cerrena unicolor during solid-state fermentation on ash sawdust-based medium. Acta Biochimica Polonica, 66(4), 419-425, https://doi.org/10.18388/abp.2019_2823
7. Bancerz R., Osińska-Jaroszuk M., Jaszek M., Sulej J., Wiater A., Matuszewska A., and Rogalski J. (2018) Fungal polysaccharides as a water-adsorbing material in esters production with the use of lipase from Rhizomucor variabilis. International journal of biological macromolecules, 118, 957-964, https://doi.org/10.1016/j.ijbiomac.2018.06.162
8. Osińska-Jaroszuk M., Jaszek M., Starosielec M., Sulej J., Matuszewska A., Janczarek M., Bancerz R., Wydrych J., Wiater A. and Jarosz-Wilkołazka A. (2018). Bacterial exopolysaccharides as a modern biotechnological tool for modification of fungal laccase properties and metal ion binding. Bioprocess and biosystems engineering, 41(7), 973-989, https://doi.org/10.1007/s00449-018-1928-x
9. Janusz G., Pawlik A., Sulej J., Świderska-Burek U., Jarosz-Wilkołazka A., and Paszczyński A. (2017). Lignin degradation: microorganisms, enzymes involved, genomes analysis and evolution. FEMS microbiology reviews, 41(6), 941-962, https://doi.org/10.1093/femsre/fux049
10. Statkiewicz M., Matuszewska A., Jaszek M., Janusz G., Osińska M., Sulej J., Stefaniuk D., Mikula M. and Ostrowski J. (2017) Antimelanomic effects of high-and low-molecular weight bioactive subfractions isolated from the mossy maze mushroom, Cerrena unicolor (Agaricomycetes). International Journal of Medicinal Mushrooms, 19(7), DOI: 10.1615/IntJMedMushrooms.2017021241
11. Osińska-Jaroszuk M., Jaszek M., Sulej J., Stefaniuk D., Urbaniak M., Siwulski M. and Janusz G., (2016) Complex biochemical analysis of fruiting bodies from newly isolated Polish Flammulina velutipes strains. Polish J Microbiol, 65, pp.295-305. DOI: 10.5604/17331331.1215609
12. Matuszewska A., Karp M., Jaszek M., Janusz G., Osińska‑Jaroszuk M., Sulej J., Stefaniuk D., Tomczak W. and Giannopoulos K. (2016) Laccase purified from Cerrena unicolor exerts antitumor activity against leukemic cells. Oncology letters, 11(3), pp.2009-2018.  https://doi.org/10.3892/ol.2016.4220
13. Janusz G., Sulej J., Jaszek M. and Osińska-Jaroszuk M. (2016) Effect of different wavelengths of light on laccase, cellobiose dehydrogenase, and proteases produced by Cerrena unicolor, Pycnoporus sanguineus and Phlebia lindtneri. Acta Biochimica Polonica, 63(2), pp.223-228. DOI: https://doi.org/10.18388/abp.2015_1235
14. Bancerz R., Osińska‐Jaroszuk M., Jaszek M., Janusz G., Stefaniuk D., Sulej J., Janczarek M., Jarosz‐Wilkołazka A. and Rogalski J. (2016) New alkaline lipase from Rhizomucor variabilis: Biochemical properties and stability in the presence of microbial EPS. Biotechnology and applied biochemistry, 63(1), pp.67-76, https://doi.org/10.1002/bab.1351
15. Mizerska-Dudka M., Jaszek M., Błachowicz A., Rejczak T.P., Matuszewska A., Osińska-Jaroszuk M., Stefaniuk D., Janusz G., Sulej J. and Kandefer-Szerszeń M. (2015) Fungus Cerrena unicolor as an effective source of new antiviral, immunomodulatory, and anticancer compounds. International journal of biological macromolecules, 79, pp.459-468, https://doi.org/10.1016/j.ijbiomac.2015.05.015
16. Sulej J., Janusz G., Osińska-Jaroszuk M., Rachubik P., Mazur A., Komaniecka I., Choma A. and Rogalski J., 2015. Characterization of cellobiose dehydrogenase from a biotechnologically important Cerrena unicolor strain. Applied biochemistry and biotechnology, 176(6), pp.1638-1658, https://doi.org/10.1007/s12010-015-1667-2