Research areas:
• Mechanism of retention in RP LC,
• Predicting lipophilic and biological properties of bioactive compounds via RP LC,
• QSRRs and QRARs methodology
Didactic activity: Physical chemistry (L), Chromatography (T), Physical chemistry (LB), Chromatography (LB)
Publications:
1.M. Janicka, M. Sztanke, K, Sztanke, Predicting the Blood-Brain Barrier Permeability of New Drug-Like Compounds via HPLC with Various Stationary Phases, Molecules, 25(3) (2020) 487; doi:10.3390/molecules25030487;
2.M. Sztanke, J. Rzymowska, M. Janicka, K. Sztanke, Two novel classes of fused azaisocytosine-containing congeners as promising drug candidates: Design, synthesis as well as in vitro, ex vivo and in silico studies, Bioorganic Chemistry, 95 (2020) 103480;
3.M. Sztanke, J. Rzymowska, M. Janicka, K. Sztanke, Synthesis, structure confirmation, identification of in vitro antiproliferative activities and correlation of determined lipophilicity parameters with in silico bioactivity descriptors of two novel classes of fused azaisocytosine-like congeners, Arab. J. Chem, 12(8) (2019) 5302-5324;
4.M. Sztanke, J. Rzymowska, M. Janicka, K. Sztanke, Synthesis, structure elucidation, determination of antiproliferative activities, lipophilicity indices and pharmacokinetic properties of novel fused azaisocytosine-like congeners, Arab. J. Chem, 12(8) (2019) 4044-4064;
M. Sztanke, T. Tuzimski, M. Janicka, K. Sztanke, Structure–retention behaviour of biologically active fused 1,2,4-triazinones – Correlation with in silico molecular properties, Eur. J. Pharm. Sci., 68 (2015) 114-126.
