dr hab. Małgorzata Janicka

Position
professor MCSU, M.Sc. 1982 (MCSU Lublin); Ph.D. 1993 (MCSU Lublin); Habilitation 2014 (MCSU Lublin)
Units
KATEDRA CHEMII FIZYCZNEJ
Telephone number
81 537 55 39
E-mail address
Show
Link do Bazy Wiedzy
Małgorzata Janicka
Consultation
Wednesday, 11-13, room number 239

Address

Pl. Marii Curie- Skłodowskiej 3
20-031 Lublin

Scientific Activity

Research areas:

• Mechanism of retention in RP LC,

• Predicting lipophilic and biological properties of bioactive compounds via RP LC,

• QSRRs and QRARs methodology

Didactic activity: Physical chemistry (L), Chromatography (T), Physical chemistry (LB), Chromatography (LB)

Publications:

1.M. Janicka, M. Sztanke, K, Sztanke, Predicting the Blood-Brain Barrier Permeability of New Drug-Like Compounds via HPLC with Various Stationary Phases, Molecules, 25(3) (2020) 487; doi:10.3390/molecules25030487;

2.M. Sztanke, J. Rzymowska, M. Janicka, K. Sztanke, Two novel classes of fused azaisocytosine-containing congeners as promising drug candidates: Design, synthesis as well as in vitro, ex vivo and in silico studies, Bioorganic Chemistry, 95 (2020) 103480;

3.M. Sztanke, J. Rzymowska, M. Janicka, K. Sztanke, Synthesis, structure confirmation, identification of in vitro antiproliferative activities and correlation of determined lipophilicity parameters with in silico bioactivity descriptors of two novel classes of fused azaisocytosine-like congeners, Arab. J. Chem, 12(8) (2019) 5302-5324;

4.M. Sztanke, J. Rzymowska, M. Janicka, K. Sztanke, Synthesis, structure elucidation, determination of antiproliferative activities, lipophilicity indices and pharmacokinetic properties of novel fused azaisocytosine-like congeners, Arab. J. Chem, 12(8) (2019) 4044-4064;

M. Sztanke, T. Tuzimski, M. Janicka, K. Sztanke, Structure–retention behaviour of biologically active fused 1,2,4-triazinones – Correlation with in silico molecular properties, Eur. J. Pharm. Sci., 68 (2015) 114-126.