Research fields

influence of electrostatic and magnetic fields on interactions at interfaces

the research is carried out using the liquid chromatography method. By analyzing the changes in the retention of substances in the fields (electrostatic and magnetic) in relation to the retention of substances in analogous systems without fields, it is possible to draw conclusions about the influence of the magnetic or electrostatic field on the interaction at the interface. The tests are carried out in the RP, NP systems.

 The use of chromatographic methods to determine the biological activity of a substance.

The research is aimed at determining descriptors of biological activity of compounds, using various chromatographic methods, in systems imitating biological systems. The subjects are conducted in the RP, MLC, BMC systems and in systems with chromatographic columns with fillings that correspond to the secondary syntax of oranism - RP-IAM, Chol, etc. columns.

 The use of magnetic nanoparticles as carriers of biological substances and for the isolation of compounds from natural matrices

The research is aimed at determining the usefulness of magnetic nanoparticles as drug carriers, especially those dedicated to the treatment of specific organs. In addition, the possibilities of using magnetic nanoparticles to isolate pollutants from industrial wastewater are being investigated.

Publications   

1. K.E. Stepnik, I. Malinowska, M. Maciejewska,

A new application of micellar liquid chromatography in the determination of free ampicillin concentration in the drug - human serum albumin standard solution in comparison with the adsorption mehod Talanta 153 (2016) s.1-7; DOI: 10.1016/j.talanta.2016.02.045              

2. I.Malinowska, M.Studziński, Niezabitowska K., H.Malinowski

Planar Electrochromatography and Thin-Layer Chromatography of Tropane Alkaloids from Datura innoxia Mill. Extract in Pseudo-Reversed-Phase Systems”,

JPC-Journal of Planar Chromatography Modern TLC” 29 (2016) pp. 38-44,

3. K.E.Stępnik, I. Malinowska

Determination of binding properties of ampicillin in drug-human serum albumin standard solution using N-vinylpyrrolidone copolymer combined with the micellar systems,

Talanta, 162 (2017) s. 241-248, DOI: 10.1016/j.talanta.2016.09.054;

4. K. Stepnik, I. Malinowska

Skin–mimetic chromatography for prediction of human percutaneous absorption of biologically active compounds occurring in medicinal plant extracts,

Biomedical Chromatography 4 (2017) 3922, DOI: 10.1002/bmc.3922

5. I.Malinowska, A. Wronka, W Ferenc

HPTLC and magnetochromatography of new complexes of carboxylates with transition metals or rare earth elements and their ligands –study of lipophilicity: Lipophilicity of new complexes of carboxylates

Biomedical Chromatography 31 (5) (2017), DOI: 10.1002/bmc.3872.

6. I. Malinowska, M. Studziński, H. Malinowski

Retention and Separation Changes of Ternary and Quaternary Alkaloids from Chelidonium majus L. by TLC Under the Influence of External Magnetic Field

Chromatographia 80 (2017) s. 923-930, DOI:10.1007/s10337-017-3293-3  IF=1,401   

7. I. Malinowska, M. Studziński, H. Malinowski

Thin-Layer Chromatography in Moderate Strength Magnetic Fields

JPC – Journal of Planar Chromatography – Modern TLC 30 (2017) s.405-410

8. I .Malinowska, M. Studziński, H.Malinowski, J.Matysiak

Thin-layer chromatography of some derivatives of 2-2,4-dihydroxyphenyl) 1,2,4-thiadiazoles in magnetic field

JPC- Journal of Planar Chromatography- Moderen TLC 31(1) 2018, s.48-56,

9. Z. Witkiewicz, W Wardenecki, I.Malinowska,  Chromatografia cieczowa – teoria i praktyka, PWN Warszawa 2019