The adressbook

dr hab. Rafał Luchowski

Position
professor UMCS
Units
KATEDRA BIOFIZYKI
Telephone number
81 537-62-47 lub 61-51
E-mail address
Show
Webpage
ORCID iD: 0000-0003-1156-8059
https://biofizyka.umcs.pl/
Link do Bazy Wiedzy
Rafał Luchowski
Consultation
Monday 10-11 a.m.

Personal information

My research involves molecular spectroscopy and microscopy techniques in application to biophysical problems.


Scientific Activity

I'm co-author of selected following scientific papers:

1.    Raut, S., Rich, R., Fudala, R., Butler, S., Kokate, R., Gryczynski, Z., Luchowski, R., Gryczynski, I.; Resonance energy transfer between fluorescent BSA protected Au nanoclusters and organic fluorophores. Nanoscale, 2014, 6, 385-391, 10.1039/c3nr03886f.


2.    Starzyk, J., Gruszecki, M., Tutaj, K., Luchowski, R., Szlazak, R., Wasko, P., Grudzinski, W., Czub, J., Gruszecki, W.I.; Self-Association of Amphotericin B: Spontaneous Formation of Molecular Structures Responsible for the Toxic Side Effects of the Antibiotic. J. Phys. Chem. B, 2014, 118, 13821-13832, 10.1021/jp510245n.

3.    Janik E., Bednarska J., Zubik M., Sowinski K., Luchowski R., Grudzinski W., Gruszecki W.I.; Is It Beneficial for the Major Photosynthetic Antenna Complex of Plants To Form Trimers? J Phys Chem B. 2015, 119(27), 8501–8508.

4.    Tutaj K., Szlazak R., Starzyk J., Wasko P., Grudzinski W., Gruszecki W.I., Luchowski R.; The orientation of the transition dipole moments of a polyene antibiotic Amphotericin B under UV-VIS studies. J Photochem Photobiol B-Biol. 2015, 151, 83–88.

5.    Gruszecki W.I., Kulik A.J., Janik E., Bednarska J., Luchowski R., Grudzinski W., Dietler G.; Nanoscale resolution in infrared imaging of protein-containing lipid membranes. Nanoscale. 2015, 7(35), 14659–14662.

6.    Gruszecki W.I., Luchowski R., Zubik M., Grudzinski W.; Photothermal Microscopy: Imaging of Energy Dissipation From Photosynthetic Complexes. Anal Chem. 2015, 87(19), 9572–9575.

7.    Janik, E., Bednarska, J., Zubik, M., Sowinski, K., Luchowski, R., Grudzinski, W., Matosiuk, D., Gruszecki, W.I.; The xanthophyll cycle pigments, violaxanthin and zeaxanthin, modulate molecular organization of the photosynthetic antenna complex LHCII. Arch Biochem Biophys. 2016, 592, 1-9

8.    Tutaj, K., Szlazak, R., Szalapata, K., Starzyk, J., Luchowski, R., Grudzinski, W., Osinska-Jaroszuk, M., Jarosz-Wilkolazka, A., Szuster-Ciesielska, A.,  Gruszecki, W.I.; Amphotericin B-silver hybrid nanoparticles: synthesis, properties and antifungal activity. Nanomedicine : nanotechnology, biology, and medicine. 2016, 12(4), 1095-1103, DOI:10.1016/j.nano.2015.12.378.

9.    Palusinska-Szysz, M., Zdybicka-Barabas, A., Reszczynska, E., Luchowski, R., Kania, M., Gisch, N., Waldow, F., Mak, P., Danikiewicz, W., Gruszecki, W.I. Cytrynska, M.; The lipid composition of Legionella dumoffii membrane modulates the interaction with Galleria mellonella apolipophorin III. Biochimica et Biophysica Acta. 2016, 1861, 617–629.

10.    Grudzinski, W., Janik, E., Bednarska, J., Welc, R., Zubik, M., Sowinski, K., Luchowski, R., Gruszecki, W.I.; Light-driven reconfiguration of a xanthophyll violaxanthin in the photosynthetic pigment−protein complex LHCII: A resonance Raman study. J Phys Chem B. 2016, 19, 4373-4382.

11.    Grudzinski, W., Krzeminska, I.; Luchowski, R., Nosalewicz, A., Gruszecki, W.I.; Strong-light-induced yellowing of green microalgae Chlorella: A study on molecular mechanisms of the acclimation response. Algal Research Biomass, Biofuels and Bioproducts. 2016, 16, 245-254. DOI: 10.1016/j.algal.2016.03.021

12.    Grudzinski, W., Sagan, J.; Welc, J.; Luchowski, R., Gruszecki, W.I.; Molecular organization, localization and orientation of antifungal antibiotic Amphotericin B in a single lipid bilayer. Scientific Reports. 2016, 6, 32780. DOI: 10.1038/srep32780

13.    Welc, R., Luchowski, R., Grudzinski, W., Puzio, M., Sowinski, K., Gruszecki, W.I.; A key role of xantophylls that are not embedded in proteins in regulation of the photosynthetic antenna function in plants, reveald by monomolecular layer studies. J Phys Chem B. 2016, DOI: 10.1021/acs.jpcb.6b10393

14.    Janik, E., Bednarska, J., Zubik, M., Luchowski, R., Mazur, R., Sowinski, K., Grudzinski, W., Garstka, M., Gruszecki, W.I.; A chloroplast „wake up” mechanism: Illumination with weak light activates the photosynthetic antenna function in dark-adapted plants. J Plant Physiology. 2017, 210, 1–8.

15.    Janik, E., Bednarska J., Sowinski K., Luchowski R., Zubik M., Grudzinski W., Gruszecki W.I.; Light-Induced Formation of Dimeric LHCII. Photosynthesis Research 2017, 132, 265–76. doi:10.1007/s11120-017-0387-6.

16.    Drozdziel, A., Turek, M., Pyszniak, K., Prucnal, S., Luchowski, R., Grudzinski, W., Klimek-Turek, A., Partyka, J.; Modification of Optical and Electrical Properties of PET Foils by He+, Ne+ and Ar+ Implantation. Acta Physics Polonica A 2017, 132: 264-269, DOI: 10.12693/APhysPolA.132.264

17.    Grudzinski, W., Nierzwicki, L., Welc, R., Reszczynska, E., Luchowski, R., Czub, J., and Gruszecki, W.I. ; Localization and Orientation of Xanthophylls in a Lipid Bilayer. Scientific Reports 2017, 7: 9619, DOI: 10.1038/s41598-017-10183-7

18.    Grudzinski, W., Piet, M., Luchowski, R., Reszczynska, E., Welc, R., Paduch, R., and Gruszecki, W.I. ; Different molecular organization of two carotenoids, lutein and zeaxanthin, in human colon epithelial cells and colon adenocarcinoma cells. Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 2018, 188, 57–63.

19.    Plazinska, A., Plazinski, W., Luchowski, R., Wnorowski, A., Grudzinski, W., and Gruszecki, W.I. ; Ligand-induced action of the W286(6.48) rotamer toggle switch in the beta(2)-adrenergic receptor. Phys. Chem. Chem. Phys. 2018, 20, 581–594.

20.    Matwijczuk, A., Janik, E., Luchowski, R., Niewiadomy, A., Gruszecki, W.I. and Gagos, M.; Spectroscopic studies of the molecular organization of 4-([1,2,4] triazolo [4,3-a] pyridin-3-yl)-6-methylbenzene-1,3-diol in selected solvents. J. Luminesc. 2018, 194, 208–218.

21.    Pawlikowska-Pawlega, B., Kapral, J., Gawron, A., Stochmal, A., Zuchowski, J., Pecio, L., Luchowski, R., Grudzinski, W., and Gruszecki, W.I.; Interaction of a quercetin derivative - lensoside Aβ with liposomal membranes. BBA - Biomembranes. 2018, 1860, 292–299.

(22)     Niewiadomska, E.; Brueckner, K.; Mulisch, M.; Kruk, J.; Orzechowska, A.; Pilarska, M.; Luchowski, R.; Gruszecki, W. I.; Krupinska, K. Lack of Tocopherols Influences the PSII Antenna and the Functioning of Photosystems under Low Light. J. Plant Physiol. 2018, 223, 57–64.


(23)     Tchorzewska, D.; Luchowski, R.; Gruszecki, W.; Winiarczyk, K. Comparative Studies of Live Tapetum Cells in Sterile Garlic (Allium Sativum) and Fertile Leek (Allium Ampeloprasum) Using the Fluorescence Lifetime Imaging Analytical Method. S. Afr. J. Bot. 2018, 117, 222–231.


(24)     Grela, E.; Wieczor, M.; Luchowski, R.; Zielinska, J.; Barzycka, A.; Grudzinski, W.; Nowak, K.; Tarkowski, P.; Czub, J.; Gruszecki, W. I. Mechanism of Binding of Antifungal Antibiotic Amphotericin B to Lipid Membranes: An Insight from Combined Single-Membrane Imaging, Microspectroscopy, and Molecular Dynamics. Mol. Pharm. 2018, 15 (9), 4202–4213.


(25)     Grela, E.; Piet, M.; Luchowski, R.; Grudzinski, W.; Paduch, R.; Gruszecki, W. I. Imaging of Human Cells Exposed to an Antifungal Antibiotic Amphotericin B Reveals the Mechanisms Associated with the Drug Toxicity and Cell Defence. Sci Rep 2018, 8, 14067.


(26)     Zdybicka-Barabas, A.; Stączek, S.; Pawlikowska-Pawlęga, B.; Mak, P.; Luchowski, R.; Skrzypiec, K.; Mendyk, E.; Wydrych, J.; Gruszecki, W. I.; Cytryńska, M. Studies on the Interactions of Neutral Galleria Mellonella Cecropin D with Living Bacterial Cells. Amino Acids 2018.